PROJECT HIGHLIGHTS Governance Organization SHS - Sunnybrook Medical Services Alternative Funding Plan Association Project Title SHS-21-006 – Prone positioning for patients on medical wards with COVID-19: a multicentre, international, pragmatic randomized trial Project Highlights We aimed to assess the effects of prone positioning in reducing the risk of respiratory...
Prevention and Treatment
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CONvalescent Plasma for COVID-19 Research Trial (CONCOR-1 trial)
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PROJECT HIGHLIGHTS Governance Organization SHS - Sunnybrook Medical Services Alternative Funding Plan Association Project Title SHS-21-001 – CONvalescent Plasma for COVID-19 Research Trial (CONCOR-1 trial) Project Highlights This trial randomized 940 patients at 72 hospitals in Canada, the United States, and Brazil, between May 2020 and January 2021. From...
Prone positioning for patients on general medical wards with COVID-19: A multicenter pragmatic randomized trial [COVID-PRONE]
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PROJECT HIGHLIGHTS Governance Organization SMH - St. Michael's Hospital Medical Services Association Project Title SMH-21-005 – Prone positioning for patients on general medical wards with COVID-19: A multicenter pragmatic randomized trial Project Highlights Prone positioning has been part of clinical practice since the 1970s and is considered standard of...
Evaluation and management of viral shedding and transmissibility in tears and conjunctival secretions of patients with COVID-19
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PROJECT HIGHLIGHTS Governance Organization SMH - St. Michael's Hospital Medical Services Association Project Title SMH-21-009 – Evaluation and management of viral shedding and transmissibility in tears and conjunctival secretions of patients with COVID-19 Project Highlights Introduction Conjunctivitis may be a common early sign of COVID-19. The viral shedding in...
Developing and implementing a Toronto Critical Care Research Hub (TCCRH) for conducting pandemic research to allow efficient and effective conduct for completion of pandemic research in critical care.
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PROJECT HIGHLIGHTS Governance Organization SMH - St. Michael's Hospital Medical Services Organization Project Title SMH-20-040 – Developing and implementing a Toronto Critical Care Research Hub (TCCRH) for conducting pandemic research to allow efficient and effective conduct for completion of pandemic research in critical care. Project Highlights Aim- To rapidly...
Exogenous Surfactant Administration for Patients with COVID-19: the LESSCOVID trial (the London Exogenous Surfactant Study for COVI19)
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PROJECT HIGHLIGHTS Governance Organization AMO - Academic Medical Organization of Southwestern Ontario Project Title AMO-20-031 – Exogenous Surfactant Administration for Patients with COVID-19: the LESSCOVID trial (the London Exogenous Surfactant Study for COVI19) Project Highlights London Exogenous Surfactant Study in COVID-19 Patients (LESSCOVID) Background and Rationale Over the last...
Hypercoagulation in SARS-CoV-2 infection – Conventional Coagulation Testing versus Point of Care Thromboelastography
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PROJECT HIGHLIGHTS Governance Organization AMO - Academic Medical Organization of Southwestern Ontario Project Title AMO-20-030 – Hypercoagulation in SARS-CoV-2 infection – Conventional Coagulation Testing versus Point of Care Thromboelastography Project Highlights We have been successful in procuring and implementing a thromboelastography (TEG) platform at LHSC. The TEG equipment has...
Rapid Identification of Therapeutic Targets to Optimize Care of Critically Ill COVID-19 Patients
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PROJECT HIGHLIGHTS Governance Organization AMO - Academic Medical Organization of Southwestern Ontario Project Title AMO-20-029 – Rapid Identification of Therapeutic Targets to Optimize Care of Critically Ill COVID-19 Patients Project Highlights Despite widespread vaccination, the threat of COVID-19 has not ended. Indeed, new variants continue to emerge and localized...
Multi-centre randomized controlled trial of hyperbaric oxygen therapy for COVID-19
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PROJECT HIGHLIGHTS Governance Organization TOH - The Ottawa Hospital Academic Medical Organization Project Title TOH-21-015 – Multi-centre randomized controlled trial of hyperbaric oxygen therapy for COVID-19 Project Highlights This project aimed to evaluate the effect of hyperbaric oxygen therapy (HBOT) on clinical outcome status in hypoxemic hospitalized COVID-19 patients....
Stem cell solutions for COVID-19 related acute respiratory distress syndrome
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PROJECT HIGHLIGHTS Governance Organization UOH - University of Ottawa Heart Institute Academic Medical Organization Project Title UOH-21-003 – Stem cell solutions for COVID-19 related acute respiratory distress syndrome Project Highlights Although 90% of infections with the novel coronavirus 2 (COVID-19) are mild, many patients progress to acute respiratory distress...