Melissa Parker, MD, MSc
SPECIALTY AND TITLE
Associate Professor of Pediatrics, Health Research Methods, Evidence, and Impact; Division Head, Pediatric Critical Care Medicine
McMaster Children’s Hospital
AREA OF RESEARCH
Dr. Parker holds certification in Pediatrics, Pediatric Emergency Medicine, and Pediatric Critical Care Medicine as well as research training in health research methodology. Her main area of clinical and research interest is resuscitation science. SQUEEZE investigated a fluid-sparing resuscitation strategy vs usual care in children with septic shock, with linked translational research investigating early sepsis biomarkers, and qualitative research exploring experiences with deferred consent.
MAJOR CONTRIBUTIONS TO SCIENCE AND/OR HEALTH CARE DELIVERY
The SQUEEZE Trial is the first trial to be endorsed by both the Canadian Critical Care Trials Group and Pediatric Emergency Research Canada. Resuscitation research poses unique challenges including timely patient identification and enrolment, and continuation of interventions across care areas. SQUEEZE is also the first pediatric trial in Canada to utilize an exception to consent (deferred consent) model, and many of the study processes developed for use in SQUEEZE have been adopted for use in other pediatric trials. Research linked to SQUEEZE has also generated new knowledge about substitute decison-maker (parent/guardian) experiences with the deferred consent process.